High-dose cyclophosphamide in the treatment of refractory lymphomas and solid tumor malignancies
β Scribed by Carolyn Collins; Joanne Mortimer; Robert B. Livingston
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 527 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0008-543X
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Seventeen patients less than or equal to 20 years of age with newly diagnosed (n = 10) or recurrent (n = 7) malignant gliomas (anaplastic astrocytoma and glioblastoma multiforme) were treated with cyclophosphamide in association with hematopoietic cytokines (GM-CSF or G-CSF). Cyclophosphamide was gi
## Abstract Cyclophosphamide (CY) in a total dose of 120 mg/kg was given over 2 days on one to three occasions to 12 patients with a variety of nonlymphoid solid tumors. Two of 10 patients with measurable disease had a partial response. One had embryonal rhabdomyosarcoma and the other had ovarian c