Prospects for Admixture Mapping of Complex Traits
โ Scribed by Paul M. McKeigue
- Book ID
- 117854564
- Publisher
- American Society of Human Genetics
- Year
- 2005
- Tongue
- English
- Weight
- 197 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/426949
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Statistical genetic mapping methods are powerful tools for "nding genes that contribute to complex human traits. Mapping methods combine knowledge of the biological mechanisms of inheritance and the randomness inherent in those mechanisms to locate, with increasing precision, trait genes on the huma
## Abstract Models for complex and quantitative traits that involve multiple, possibly interacting, genes are described. Methods of linkage analysis are developed that utilize special features of these models, and their power is compared with that of simple genome scans that ignore these special fe