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Prospective, open-label trial of rituximab in childhood systemic lupus erythematosus

โœ Scribed by Emma Jane MacDermott; Thomas J. A. Lehman

Book ID
107553851
Publisher
Springer
Year
2006
Tongue
English
Weight
65 KB
Volume
8
Category
Article
ISSN
1523-3774

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## Abstract ## Objective B cells are likely to contribute to the pathogenesis of systemic lupus erythematosus (SLE), and rituximab induces depletion of B cells. The Exploratory Phase II/III SLE Evaluation of Rituximab (EXPLORER) trial tested the efficacy and safety of rituximab versus placebo in p