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Properties of Water Molecules in the Active Site Gorge of Acetylcholinesterase from Computer Simulation

โœ Scribed by Henchman, Richard H.; Tai, Kaihsu; Shen, Tongye; McCammon, J. Andrew


Book ID
118515079
Publisher
Biophysical Society
Year
2002
Tongue
English
Weight
854 KB
Volume
82
Category
Article
ISSN
0006-3495

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๐Ÿ“œ SIMILAR VOLUMES


Rapid binding of a cationic active site
โœ Sylvia Tara; Adrian H. Elcock; Paul D. Kirchhoff; James M. Briggs; Zoran Radic; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 133 KB ๐Ÿ‘ 2 views

It is known that anionic surface residues play a role in the long-range electrostatic attraction between acetylcholinesterase and cationic ligands. In our current investigation, we show that anionic residues also play an important role in the behavior of the ligand within the active site gorge of ac