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(37) Ligand-induced conformational changes in residues flanking the active site gorge of acetylcholinesterase

✍ Scribed by Leo Pezzementi; Jianxin Shi; David A. Johnson; Zoran Radic; Aileen Boyd; Palmer Taylor


Book ID
113517283
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
92 KB
Volume
157-158
Category
Article
ISSN
0009-2797

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Ligand-Induced conformational changes in
✍ Jianhua Wu; Stathis Frillingos; John Voss; H. Ronald Kaback πŸ“‚ Article πŸ“… 1994 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 848 KB

## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 β†’ Cys permease, lactose transport is inactivated by either __N__‐ethy