✦ LIBER ✦

A Novel Computational Analysis of Ligand-Induced Conformational Changes in the ATP Binding Sites of Cyclin Dependent Kinases

✍ Scribed by Subramanian, Jyothi; Sharma, Somesh; B-Rao, Chandrika

Book ID: 120432040
Publisher: American Chemical Society
Year: 2006
Tongue: English
Weight: 400 KB
Volume: 49
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm060172s

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Ligand-Induced conformational changes in

Ligand-Induced conformational changes in the lactose permease of escherichia coli: Evidence for two binding sites

✍ Jianhua Wu; Stathis Frillingos; John Voss; H. Ronald Kaback 📂 Article 📅 1994 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 848 KB

## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 → Cys permease, lactose transport is inactivated by either __N__‐ethy

Evidence for a Mg2+-Induced Conformation

Evidence for a Mg2+-Induced Conformational Change at the ATP-Binding Site of (Na++ K+)-ATPase Demonstrated with a Photoreactive ATP-Analogue

✍ Gerold REMPETERS; Wilhelm SCHONER 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 649 KB

Novel mutation in the ATP-binding site o

Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family

✍ Martina Olivero; Guido Valente; Alberto Bardelli; Paola Longati; Norma Ferrero; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 123 KB

Germline mutations in the tyrosine-kinase domain of the MET proto-oncogene were found in patients suffering from the hereditary predisposition to develop multiple papillary renal-cell carcinomas (hereditary PRCC, HPRCC). PRCCs are often multiple and bilateral even in patients without a family histor

Paromomycin binding induces a local conf

Paromomycin binding induces a local conformational change in the A-site of 16 s rRNA

✍ Dominique Fourmy; Satoko Yoshizawa; Joseph D. Puglisi 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 521 KB

Ligand binding site interaction in adeno

Ligand binding site interaction in adenosine cyclic 3',5'-monophosphate-dependent protein kinase catalytic subunit: circular dichroic evidence for intramolecular transmission of conformational change

✍ Reed, Jennifer; Kinzel, Volker 📂 Article 📅 1984 🏛 American Chemical Society 🌐 English ⚖ 748 KB

Mapping the ATP-Binding Site in the Cata

Mapping the ATP-Binding Site in the Catalytic Subunit of A denosine-3′:5′-monophosphate-Dependent Protein Kinase : Spatial Relationship with the ATP Site of the Undissociated Enzyme

✍ Jürgen HOPPE; Wolfgang FREIST; Rainer MARUTZKY; Shmuel SHALTIEL 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 519 KB