Promotion of photodynamic therapy-induced apoptosis by stress kinases
✍ Scribed by Xue, Liang-yan; He, Jin; Oleinick, Nancy L
- Book ID
- 110015952
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 708 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1350-9047
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📜 SIMILAR VOLUMES
Numerous new photosensitizers are now in various stages of trials demonstrating the broad applicability of Photodynamic therapy (PDT). However, only a handful of photosensitizers have received regulatory approval. Lack of effective photosensitizers has become a major limit for extensive application
## Abstract ## Background and Objectives This study was designed to examine modes of cell death after photodynamic therapy (PDT). ## Study Design Murine leukemia L1210 cells and human prostate Bax‐deficient DU145 cells were examined after PDT‐induced photodamage to the endoplasmic reticulum (ER)
## Abstract ## Background and Objectives Photodynamic therapy (PDT) induces cell death through a laser light‐activated photosensitizer and is a treatment option for tumors resistant to radio‐ and chemo‐therapy. ## Study Design/Materials and Methods We investigated whether m‐THPC‐PDT induces cell