Photodynamic therapy: A mitochondrial inducer of apoptosis
โ Scribed by Kessel, David; Luo, Yu
- Book ID
- 110015849
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 352 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1350-9047
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๐ SIMILAR VOLUMES
Numerous new photosensitizers are now in various stages of trials demonstrating the broad applicability of Photodynamic therapy (PDT). However, only a handful of photosensitizers have received regulatory approval. Lack of effective photosensitizers has become a major limit for extensive application
## Abstract ## Background and Objectives Photodynamic therapy (PDT) induces cell death through a laser lightโactivated photosensitizer and is a treatment option for tumors resistant to radioโ and chemoโtherapy. ## Study Design/Materials and Methods We investigated whether mโTHPCโPDT induces cell
## Abstract ## Background and Objectives This study was designed to examine modes of cell death after photodynamic therapy (PDT). ## Study Design Murine leukemia L1210 cells and human prostate Baxโdeficient DU145 cells were examined after PDTโinduced photodamage to the endoplasmic reticulum (ER)
## Abstract Methylene blue (MB), a widely studied reagent, is investigated in this work for its usage in photodynamic therapy (PDT). PDT has been proved to be highly effective in the treatment of different types of cancers. Previous studies showed MB has both high affinity for mitochondria and high