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Promotion of HL-60 cell differentiation by 1,25'dihydroxyvitamin D3 regulation of protein kinase C levels and activity

โœ Scribed by Quintin Pan; John Granger; Timothy D O'Conneu; Martha J Somerman; Robert U Simpson


Book ID
119407389
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
726 KB
Volume
54
Category
Article
ISSN
0006-2952

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Activation of ERK1 and ERK2 protein kinases has been implicated in diverse cellular processes, including the control of cell proliferation and cell differentiation (Marshall [1995] Cell 80:179). In human myeloblastoid leukemia HL60 cells rapid (ca. 15 min) but transient activation of ERK1/2 has been