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Reversibility of monocytic differentiation of HL-60 cells by 1α,25 dihydroxyvitamin D3

✍ Scribed by Shigeru Tomoyasu; Kunihiko Fukuchi; Kazuyuki Watanabe; Hideyuki Ueno; Yasuharu Hamano; Jun-ich Hisatake; Ken-ichiro Hino; Kunihide Gomi; Nobuyoshi Tsuruoka


Book ID
114119092
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
837 KB
Volume
21
Category
Article
ISSN
0145-2126

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The effect of inhibitors of RNA synthesis on 1,25(OHI2 vitamin D3-induced monocytic differentiation was studied in a well-differentiating clone AB 47 of HL 60 cells. The concentrations of these inhibitors were chosen to permit the rnaintenance of cell viability for at least 48 hours, and resulted in