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Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

✍ Scribed by Esteller, M.

Book ID: 118012392
Publisher: Oxford University Press
Year: 2000
Tongue: English
Weight: 170 KB
Volume: 92
Category: Article
ISSN: 0027-8874
DOI: 10.1093/jnci/92.7.564

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## Abstract Comparative genomic hybridization (CGH) analysis has shown that chromosome 5q deletions are the most frequent aberration in breast tumors from __BRCA1__ mutation carriers. To map the location of putative 5q tumor suppressor gene(s), 26 microsatellite markers covering chromosome 5 were u