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Proinflammatory cytokines contribute to development and function of regulatory T cells in type 1 diabetes

✍ Scribed by Thomas, Helen E.; Graham, Kate L.; Chee, Jonathan; Thomas, Ranjeny; Kay, Thomas W.; Krishnamurthy, Balasubramanian


Book ID
124102212
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
523 KB
Volume
1283
Category
Article
ISSN
0890-6564

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## Abstract ## Background Heparanase is an endo‐β‐D‐glucuronidase that cleaves heparan sulfate saccharide chains. The enzyme promotes cell adhesion, migration and invasion, and was shown to play a significant role in cancer metastasis and angiogenesis. ## Methods The present study focuses on the