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Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice

✍ Scribed by Adi Mor; Yoel Kloog; Gad Keren; Jacob George


Book ID
113588311
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
491 KB
Volume
616
Category
Article
ISSN
0014-2999

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Heparanase prevents the development of t
✍ Menachem Bitan; Lola Weiss; Michael Zeira; Shoshana Reich; Orit Pappo; Israel Vl πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 216 KB

## Abstract ## Background Heparanase is an endo‐β‐D‐glucuronidase that cleaves heparan sulfate saccharide chains. The enzyme promotes cell adhesion, migration and invasion, and was shown to play a significant role in cancer metastasis and angiogenesis. ## Methods The present study focuses on the