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Prognostic Significance of Regulators of Cell Cycle and Apoptosis, p16INK4a, p53, and bcl-2 in Primary Mucosal Melanomas of the Head and Neck

✍ Scribed by Manju L. Prasad, Snehal G. Patel, Jatin P. Shah, Stacy Hoshaw-Woodard, Klaus J. Busam

Book ID
113095035
Publisher
Springer US
Year
2011
Tongue
English
Weight
529 KB
Volume
6
Category
Article
ISSN
1936-055X

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## Abstract Besides well‐known risk factors such as tobacco use and alcohol consumption, oncogenic human papillomavirus (HPV) infection also has recently been suggested to promote head and neck tumorigenesis. HPV is known to cause cancer by inactivation of cell cycle regulators p53 and pRb via expr