INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck
β Scribed by Anette Weber; Ulf Bellmann; Friedrich Bootz; Christian Wittekind; Andrea Tannapfel
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 199 KB
- Volume
- 441
- Category
- Article
- ISSN
- 1432-2307
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## Background: A critical factor for successful organ preservation treatment in head and neck cancer may be selecting tumors that respond to chemotherapy and radiation. previous results in patients indicated that tumors that overexpressed p53 were more sensitive to chemotherapy than those that did