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Prognostic implications of monosomy 3 in uveal melanoma

✍ Scribed by N Bornfeld; G Prescher; R Becher; H Hirche; K-H Jöckel; B Horsthemke

Book ID
118561210
Publisher
The Lancet
Year
1996
Tongue
English
Weight
473 KB
Volume
347
Category
Article
ISSN
0140-6736

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## Abstract Gains and losses of chromosomes 1, 3, 6 and 8 are nonrandom chromosomal aberrations in uveal melanoma. Monosomy 3 is the most frequent abnormality and is associated with poor prognosis. To identify regions of allelic loss on the short arm of chromosome 1 and to investigate if these alte