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Prognostic cytogenetic markers in childhood acute lymphoblastic leukemia

✍ Scribed by A. Settin; M. Al Haggar; T. Al Dosoky; R. Al Baz; Nabil M. Abdelrazik; M. Fouda; S. Aref; Y. Al-Tonbary

Book ID
107597994
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
177 KB
Volume
74
Category
Article
ISSN
0019-5456

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## Abstract High hyperdiploidy (51–67 chromosomes) is the most common cytogenetic abnormality pattern in childhood B‐cell precursor acute lymphoblastic leukemia (ALL), occurring in 25–30% of such cases. High hyperdiploid ALL is characterized cytogenetically by a nonrandom gain of chromosomes X, 4,