Prognostic Criteria, Treatment and Survival in Disseminated Histiocytosis X
โ Scribed by I. R. G. TOOGOOD; W. M. ELLIS; H. EKERT
- Book ID
- 118705402
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 373 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1034-4810
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Six children received etoposide as the single agent for treatment of Langerhans cell histiocytosis (LCH; histiocytosis X). Five were less than 2 years old at diagnosis. All had multiorgan involvement; one had liver and pulmonary dysfunction. Two infants also had clinical signs of immune deficiency.
## Abstract Sixty children survived for five years after the diagnosis of histiocytosis X. Serious disabilities were seen in 50% of children whose disease involved soft tissue and bone. Late deaths from pulmonary failure were associated with opportunistic infections in two cases. Future treatment