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Histiocytosis X in children: Patterns of disease and results of treatment

✍ Scribed by Matus-Ridley, Monica ;Raney, R. Beverly ;Thawerani, Hasina ;Meadows, Anna T.

Book ID
102950792
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
616 KB
Volume
11
Category
Article
ISSN
0098-1532

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Etoposide in the treatment of six childr
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Six children received etoposide as the single agent for treatment of Langerhans cell histiocytosis (LCH; histiocytosis X). Five were less than 2 years old at diagnosis. All had multiorgan involvement; one had liver and pulmonary dysfunction. Two infants also had clinical signs of immune deficiency.

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β€œEtoposide in the treatment of six child
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Viana et al. [I] described their experience with etoposide (VP-16) as initial therapy in the management of patients with Langerhans cell histiocytosis (LCH). However, caution should be used in advocating the use of an epipodophyllotoxin as the "drug of choice" for the treatment of this disorder. Alt