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Production of vampire bat plasminogen activator DSPA α1 in CHO and insect cells

✍ Scribed by T. Petri; G. Langer; P. Bringmann; L. Cashion; S. Shallow; W.-D. Schleuning; P. Donner


Book ID
119131990
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
784 KB
Volume
39
Category
Article
ISSN
0168-1656

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A depth filter perfusion system (DFPS), equipped with a 40-pm polypropylene depth filter for cell immobilization, was used for the continuous production of tissue plasminogen activator (t-PA) from recombinant Chinese hamster ovary cells. Final cell density in the DFPS with oxygen control was 1.8x10'