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Production of Oxidative DNA Damage during the Metabolic Activation of Benzo[a]pyrene in Human Mammary Epithelial Cells Correlates with Cell Killing

✍ Scribed by Steven A. Leadon, Martha R. Stampfer and Jack Bartley


Book ID
123635623
Publisher
National Academy of Sciences
Year
1988
Tongue
English
Weight
810 KB
Volume
85
Category
Article
ISSN
0027-8424

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## Abstract Aryl hydrocarbon (benzo(a)pyrene) hydroxylase (AHH) activity and metabolism of benzo(a)pyrene to water‐soluble products were measured in cultures of body fibroblasts and kidney epithelial cells from different human embryos. AHH activity at 24 h after treatment with or without benz(a)ant