Production of Fab Fragments of Monoclona
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Maria B. Dainiak; Vladimir I. Muronetz; Vladimir A. Izumrudov; Igor Yu. Galaev;
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Article
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2000
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Elsevier Science
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English
⚖ 201 KB
A new method for the production of monovalent Fab fragments of antibodies has been developed. Traditionally Fab fragments are produced by proteolytic digestion of antibodies in solution followed by isolation of Fab fragments. In the case of monoclonal antibodies against inactivated subunits of glyce