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Production of monoclonal antibodies: The effect of hybridoma concentration on the yield of antibody-producing clones

โœ Scribed by Eran Hadas; Gordon Theilen

Book ID
118900808
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
256 KB
Volume
96
Category
Article
ISSN
0022-1759

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Effect of serum concentration on product
Effect of serum concentration on production of monoclonal antibodies and on shear sensitivity of a hybridoma
โœ L. Pol; G. Zijlstra; M. Thalen; J. Tramper ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 422 KB

The effect of serum content of culture medium on the specific production rate of monoclonal antibodies (Mab's) and on shear sensitivity has been studied with hybridoma's, cultured in a continuous stirred tank reactor (CSTR). No decrease in specific Mab-production was found when the serum concentrati