## Abstract Viable interspecies cytoplasmicโnuclear hybrid cells were constructed by fusion of karyoplasts prepared from the highly tumorigenic A9 mouse fibroblast cell line and cytoplasts prepared from the Detroit 532 normal human diploid cell strain. The identity of the hybrid cells was ascertain
Production of hybrid cells by fusion of human malignant tumour cells and primary mouse embryo cells
โ Scribed by J. F. Watkins
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- French
- Weight
- 818 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Hybrid cells with a subtetraploid mouse chromosome complement were produced by fusion of three types of human tumour cells with primary mouse embryo cells. The most frequently present presumptive human chromosome was 21. Numerous chromosome rearrangements were present. Some hybrid cells produced regressing tumours in mice.
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