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Production of d-[1-13C]glucose from [13C]formaldehyde and d-ribose-5-phosphate using an enzymatic system

✍ Scribed by Hidekatsu Maeda; Kohhei Takata; Atsushi Toyoda; Kunihiko Shibata


Book ID
114294452
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
450 KB
Volume
85
Category
Article
ISSN
0922-338X

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The preparation of t3C-labeled ribonucleosides starting from D-[t3C~]glucose in 45% overall yield is described. The key of this short synthetic way is the dehomologation of di-O-isopropylidene hexofuranose 2 with periodic acid and NaBI-I4 that afforded stereoselectively the labeled ribofuranose deri