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Production of 13N-labelled molecular nitrogen for pulmonary function studies

โœ Scribed by W. Vaalburg; A. Steenhoek; A. M. J. Paans; R. Peset; S. Reiffers; M. G. Woldring

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
239 KB
Volume
18
Category
Article
ISSN
0022-2135

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โœฆ Synopsis

Abstract

A method for the production of ^13^NN either as a gas or as an injectable solution is described. The method is based on the ^16^O(p,ฮฑ)^13^N reaction and water as target material. Following irradiation, the ^13^NO and ^13^NO are reduced to ^13^NH~3~, followed by NaOBr oxidation to ^13^NN. With a beam current of 1 ฮผA and 20 min irradiation time the injectable solution contained 148 MBq (4 mCi) per ml.

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