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Production of 13N-molecular nitrogen for pulmonary positron scintigraphy

✍ Scribed by Stephen C. Jones; William M. Bucelewicz; Robert A. Brissette; Rajeshwari Subramanyam; Bernard Hoop Jr.

Publisher
Elsevier Science
Year
1977
Weight
321 KB
Volume
28
Category
Article
ISSN
0020-708X

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Production of 13N-labelled molecular nit
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## Abstract A method for the production of ^13^NN either as a gas or as an injectable solution is described. The method is based on the ^16^O(p,α)^13^N reaction and water as target material. Following irradiation, the ^13^NO and ^13^NO are reduced to ^13^NH~3~, followed by NaOBr oxidation to ^13^NN

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## Abstract Taking advantage of the ^14^N(p,pn)^13^N reaction occuring during the ^14^N(p,α)^11^C carbon dioxide production, pure [^13^N]N~2~ suitable for PET ventilation studies was produced in a standard nitrogen gas target for ^11^C‐production (“carbon‐11 target”), after elimination of ^11^CO~2~