Production and activation of recombinant papain-like cysteine proteases
✍ Scribed by Dieter Brömme; Ferez S. Nallaseth; Boris Turk
- Book ID
- 117702354
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 136 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1046-2023
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📜 SIMILAR VOLUMES
## Abstract Recent characterization of multiple classes of functionalized azapeptides as effective covalent inhibitors of cysteine proteases prompted us to investigate __O__‐acyl hydroxamates and their azapeptide analogues for use as activity‐based probes (ABPs). We report here a new class of azagl
Synthetic peptides corresponding to the proregions of papain-like cysteine proteases have been shown to be good and selective inhibitors of their parental enzymes. The molecular basis for their selectivity, quite remarkable in some cases, is not fully understood. The recent determination of the crys