𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Primed-site Probing of Papain-like Cysteine Proteases

✍ Scribed by José Maria Pfizer; Irmgard Assfalg-Machleidt; Werner Machleidt; Luis Moroder; Norbert Schaschke

Book ID
106452111
Publisher
Springer Netherlands
Year
2006
Tongue
English
Weight
469 KB
Volume
13
Category
Article
ISSN
1573-3149

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Novel Aza Peptide Inhibitors and Active-
Novel Aza Peptide Inhibitors and Active-Site Probes of Papain-Family Cysteine Proteases
✍ Steven H. L. Verhelst; Martin D. Witte; Shirin Arastu-Kapur; Marko Fonovic; Matt 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB 👁 1 views

## Abstract Recent characterization of multiple classes of functionalized azapeptides as effective covalent inhibitors of cysteine proteases prompted us to investigate __O__‐acyl hydroxamates and their azapeptide analogues for use as activity‐based probes (ABPs). We report here a new class of azagl

Structural basis for specificity of papa
Structural basis for specificity of papain-like cysteine protease proregions toward their cognate enzymes
✍ Matthew R. Groves; René Coulombe; John Jenkins; Miroslaw Cygler 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 468 KB

Synthetic peptides corresponding to the proregions of papain-like cysteine proteases have been shown to be good and selective inhibitors of their parental enzymes. The molecular basis for their selectivity, quite remarkable in some cases, is not fully understood. The recent determination of the crys