𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Processing Mutations Disrupt Interactions between the Nucleotide Binding and Transmembrane Domains of P-glycoprotein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

✍ Scribed by Loo, T. W.; Bartlett, M. C.; Clarke, D. M.


Book ID
118191522
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2008
Tongue
English
Weight
516 KB
Volume
283
Category
Article
ISSN
0021-9258

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A cystic fibrosis allele encoding missen
✍ Nanette KΓ€lin; Thilo DΓΆrk; Burkhard TΓΌmmler πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 726 KB

## Communicated by Lap-Chee Tsui German cystic fibrosis (CF) chromosomes were screened for molecular lesions in exon 20 of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by chemical cleavage of mismatch. An 3884G-to-A transition was detected in two patients which leads to an e

Identification of six mutations (R31L, 4
✍ Julian Zielenski; Danuta Markiewicz; Hai Shien Chen; Keith Schappert; Anneke Sel πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 649 KB

Six new mutations have been identified in the CFTR gene. These mutations, representing three different categories-missense (R3 lL, W1098R), nonsense ( E l 104X), and frameshift (441delA, 681delC, 1461ins4)-are located in exons 2 , 4 , 5 , 9 , and 17b of the gene and presumed to cause cystic fibrosis