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Nucleotide-binding domains of human cystic fibrosis transmembrane conductance regulator: detailed sequence analysis and three-dimensional modeling of the heterodimer

✍ Scribed by I. Callebaut; R. Eudes; J.-P. Mornon; P. Lehn

Publisher
Springer
Year
2004
Tongue
English
Weight
939 KB
Volume
61
Category
Article
ISSN
1420-682X

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The interaction between the human B cell receptor CD40 and its ligand on T cells is critical for B cell proliferation and the regulation of humoral immune responses. CD40 is a member of the tumor necrosis factor receptor (TNFR) family. We report here the construction and analysis of a detailed three