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Process of building biologically based dose-response models for developmental defects

✍ Scribed by Gaylor, David W. ;Razzaghi, Mehdi

Book ID
112219392
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
773 KB
Volume
46
Category
Article
ISSN
0040-3709

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A biologically-based dose-response model for predicting developmental malformation effects from exposure to a toxic substance during pregnancy is developed. The biological basis of this model arises from the expectation of exponential growth in rodents during gestation, and the exponential growth ra