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A Biologically-Based Dose—Response Model for Developmental Toxicology

✍ Scribed by Brian G. Leroux; Wendy M. Leisenring; Suresh H. Moolgavkar; Elaine M. Faustman

Book ID
109157116
Publisher
Springer
Year
1996
Tongue
English
Weight
815 KB
Volume
16
Category
Article
ISSN
1573-9147

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A biologically-based dose-response model for predicting developmental malformation effects from exposure to a toxic substance during pregnancy is developed. The biological basis of this model arises from the expectation of exponential growth in rodents during gestation, and the exponential growth ra