Problems of chronic transfusion in sickle cell disease
โ Scribed by Dr. Armando R. Orlina; Steven D. Sosler; Mabel Koshy
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 674 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0733-2459
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The treatment of various complications of sickle cell disease has included red cell exchange in the past, and the development of automated pheresis equipment has greatly simplified such exchanges. Traditionally, the patient's red cells have been exchanged while their plasma was returned to them. Rec
The transfusion histories over a 33-month period of 50 patients with sickle cell disease were reviewed to determine the frequency of alloimmunization to red cell antigens following transfusion in these patients. There were 30 females and 20 males, aged 19--49 years. Eighteen (36%) were immunized of
## Abstract Patients with sickle cell disease (SCD) appear to be at lower risk of endocrinopathies and cardiac dysfunction than those with thalassemia major (TM). Circulating redox active iron is lower in these patients, possibly due to increased systemic inflammation and circulating cytokines. Hep
Cerebrovascular accidents (CVA) as a complication of sickle cell disease occur most frequently in childhood. Life-long transfusion prevents recurrent stroke, but inevitably leads to iron overload. Although effective chelation exists, many patients are not compliant. Erythrocytapheresis, an automated