Probabilistic intake assessment of polybrominated diphenyl ethers and omega-3 fatty acids through fish consumption

✍ Scribed by Isabelle Sioen; Maaike Bilau; Frederik Verdonck; Wim Verbeke; Jan L. Willems; Stefaan De Henauw; John Van Camp

• Book ID: 102948866
• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 926 KB
• Volume: 52
• Category: Article
• ISSN: 1613-4125
• DOI: 10.1002/mnfr.200700109

✦ Synopsis

Abstract

Food intake is one of the principal exposure routes of polybrominated diphenyl ethers (PBDEs) in humans. This study focuses on fish consumption as a PBDE exposure route. A probabilistic intake assessment of PBDEs and healthy long chain omega‐3 PUFAs (LC n‐3 PUFAs) was conducted for Belgian fish consumers in order to study the balance of the intake of LC n‐3 PUFAs and PBDEs. Based on the observed fish consumption level in the sample, the mean intake of brominated diphenyl ether (BDE)‐28, 47, 99, 100, 153, and 154 via fish was 0.85 ng/kg body weight (bw)/day and the intake of LC n‐3 PUFAs was 3.45 mg/kg bw/day, being low compared to the recommendations. Scenario analyses showed that consuming 150 g salmon twice a week is advisable to achieve the recommended LC n‐3 PUFA intake with a rather low PBDE intake. When replacing 150 g salmon by herring, the PBDE intake is higher without an increase in LC n‐3 PUFAs. In contrast, the combination of cod and salmon leads to a similar PBDE intake compared to twice a week salmon, but to a lower LC n‐3 PUFA intake. In conclusion, the methodology presented in the paper allows balancing benefits and risks related to fish consumption.