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Prion protein conversion in vitro

✍ Scribed by Surachai Supattapone

Publisher
Springer
Year
2004
Tongue
English
Weight
233 KB
Volume
82
Category
Article
ISSN
0946-2716

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Poly-L-lysine (PLL), a homopolymer of amino acid L-lysine (LL), has been frequently used for drug delivery. Here, we report that PLL is an effective agent to inhibit propagation of prions that cause fatal and incurable neurologic disorders in humans and animals, termed prion diseases. In our recent