Primer and interviews: Promises and realities of induced pluripotent stem cells
โ Scribed by Julie C. Kiefer
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 137 KB
- Volume
- 240
- Category
- Article
- ISSN
- 1058-8388
No coin nor oath required. For personal study only.
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Pluripotent stem cells have been generated from mouse and human somatic cells by viral expression of the transcription factors Oct4, Sox2, Klf4, and c-Myc. A major limitation of this technology is the use of potentially harmful genome-integrating viruses. Here, we generate mouse induced pluripotent
## Abstract Induced pluripotent stem (iPS) cells are of potential value not only for regenerative medicine, but also for disease investigation. The present study describes the development of a neutrophil differentiation system from human iPS cells (hiPSCs) and the analysis of neutrophil function an