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Primary biliary cirrhosis: The prequency of autoantibodies and the serum levels of immunoglobulins (IgG,M,A)


Book ID
118566988
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
120 KB
Volume
21
Category
Article
ISSN
0168-8278

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๐Ÿ“œ SIMILAR VOLUMES


Frequency of IgG and IgM autoantibodies
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We have previously identified four of the M2 antigens in primary biliary cirrhosis as the E2 components (dihydrolipoamide acyltransferases) of pyruvate dehydrogenase complex, branched-chain 2-0x0 acid dehydrogenase complex and 2-oxoglutarate dehydrogenase complex and the protein X component of pyruv

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Autoantibodies against inner mitochondrial membrane proteins are a hallmark of primary biliary cirrhosis. Specifically, these antimitochondrial autoantibodies recognize two polypeptides of approximately 70 and 52 kD, respectively. Although the specificity of antimitochondrial autoantibodies has been