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A comprehensive evaluation of serum autoantibodies in primary biliary cirrhosis

โœ Scribed by Nancy Agmon-Levin; Yinon Shapira; Carlo Selmi; Ori Barzilai; Maya Ram; Martine Szyper-Kravitz; Sara Sella; Bat-sheva Porat Katz; Pierre Youinou; Yves Renaudineau; Bruno Larida; Pietro Invernizzi; M. Eric Gershwin; Yehuda Shoenfeld


Book ID
116614252
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
131 KB
Volume
34
Category
Article
ISSN
0896-8411

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A major enigma of primary biliary cirrhosis (PBC) is the selective targeting of biliary cells. Our laboratory has reported that after apoptosis, human intrahepatic biliary epithelial cells (HiBECs) translocate the E2 subunit of the pyruvate dehydrogenase complex immunologically intact into apoptotic