## Abstract CD4^+^CD25^+^ regulatory T cells (Treg) appear to be critical in regulating immune responses to selfβantigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mecha
β¦ LIBER β¦
Preventing autoimmunity by regulating regulatory T-cell induction
β Scribed by Friedrich Luft
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 104 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0946-2716
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## Abstract Naturally occurring CD4^+^CD25^+^ regulatory T cells (Treg) exert an important role in mediating maternal tolerance to the fetus during pregnancy, and this effect might be regulated via maternal estrogen secretion. Although estrogen concentration in the pharmaceutical range has been sho