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Prevalent genotypes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) in spontaneously aborted embryos

✍ Scribed by Jeehyeon Bae; Seung Joo Shin; Sun Hee Cha; Dong Hee Choi; Suman Lee; Nam Keun Kim


Book ID
116469133
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
84 KB
Volume
87
Category
Article
ISSN
1556-5653

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Methylenetetrahydrofolate reductase (MTH
✍ Rady, Peter L.; Tyring, Stephen K.; Hudnall, S. David; Vargas, Trini; Kellner, L πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 36 KB πŸ‘ 2 views

The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy