Prevalence of MCPyV in Merkel cell carcinoma and non-MCC tumors
โ Scribed by Christian Andres; Benedetta Belloni; Ursula Puchta; Christian A. Sander; Michael J. Flaig
- Book ID
- 111242622
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 529 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0303-6987
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## Abstract The recently discovered human polyomavirus (MCPyV) is frequently found in Merkel cell carcinoma (MCC) tissue and is believed to be causally linked to MCC pathogenesis. While cell lines established from MCC represent a valuable tool to study the contribution of MCPyV to MCC pathogenesis,
A case of neuroendocrine skin carcinoma (Merkel cell carcinoma) with a deletion of the short arm of chromosome I (I p) as the sole chromosomal abnormality was examined. The tumor originated in the skin of the left knee of a 67-year-old man. Histopathologic study showed an undifferentiated small cell