Prevalence of Merkel cell polyomavirus in Merkel cell carcinoma
β Scribed by Duncavage, Eric J; Zehnbauer, Barbara A; Pfeifer, John D
- Book ID
- 109887781
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 344 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0893-3952
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## Abstract Merkel cell carcinoma is a rare malignancy that sometimes occurs in the skin of elderly people. Recently, a new human polyomavirus, Merkel cell polyomavirus (MCPyV) was identified in Merkel cell carcinoma. In the present study, MCPyVβDNA was detected in 6 of 11 (55%) cases of Merkel cel
## Abstract Merkel cell polyomavirus (MCPyV) was recently discovered in Merkel cell carcinoma (MCC), a clinically and pathologically heterogeneous malignancy of dermal neuroendocrine cells. To investigate this heterogeneity, we developed a tissue microarray (TMA) to characterize immunohistochemical
## Abstract Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. It has recently been reported that integration of a Merkel cell polyomavirus (MCPyV) in __receptor tyrosine phosphates type G__ (__PTPRG__) gene occurs in MCC, and that viral infections are associated with ep