Enzyme-linked immunosorbent assay (ELISA) and immunoblotting were used to define comparatively the frequency of antibodies to total histones and different histone fractions -HI, H2A, H2B, H3, and H4 -in 16 patients with idiopathic systemic lupus erythematosns. HI and H2B showed the most prominent an
✦ LIBER ✦
Prevalence of Antinucleosome Antibodies by Enzyme-Linked Immunosorbent Assays in Patients with Systemic Lupus Erythematosus and Other Autoimmune Systemic Diseases
✍ Scribed by IVANA PŮTOVÁ; C. DOSTAL; R. BECVAR
- Book ID
- 111483456
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 75 KB
- Volume
- 1109
- Category
- Article
- ISSN
- 0890-6564
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## Abstract Thirty patients with systemic lupus erythematosus (SLE( were studied over a 2.5‐year period. The group was divided into 14 patients with antibodies to Sm and a control group which failed to exhibit antibodies to Sm over the study period. The titer of antibodies to Sm fluctuated in all 1