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Prevalence of antibodies to hepatitis a antigen in sera from patients with hematological malignancies

✍ Scribed by E. Sandra McFarlane; Juan A. Embil

Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 268 KB
Volume: 8
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890080104

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The prevalence of antibodies to hepatitis A (anti‐HA) was investigated in patients attending a clinic for hematological malignancies. Patients were divided into three age groups; the number with antibodies in each group was recorded. Of the 130 patients studied, 44% of those aged 4–26, 70% of those aged 27–50, and 83% of those aged 51–76, were positive. This study identifies patients attending a clinic for hematological malignancies (ie, patients with immunologic deficiencies) as a group of people having a high prevalence of anti‐HA. In the oldest group (51–76), urban patients had a higher prevalence than rural patients — a pattern similar to that observed in elderly Red Cross blood donors in a previous study. Seroconversion was noted in six patients, three of whom seroconverted from anti‐HA‐negative to anti‐HA‐positive within 12 months of the initial visit to the clinic.

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