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Detection of IgG and IgA antibodies to epstein-barr virus membrane antigen in sera from patients with nasopharyngeal carcinoma and from normal individuals

✍ Scribed by X. X. Zhu; Y. Zeng; H. Wolf

Publisher
John Wiley and Sons
Year
1986
Tongue
French
Weight
248 KB
Volume
37
Category
Article
ISSN
0020-7136

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✦ Synopsis

IgG and IgA antibodies to Epstein-Barr virus (EBV) membrane antigen (MA) were detected in sera from 96 NPC patients and normal individuals by the indirect immunofluorescence test. For MA/IgG antibody, 100% of NPC patients were positive with a GMT of 1:439.7 and 97.9% of normal individuals were positive with a GMT of 1:94.7. In contrast, for MA/IgA antibody, 58.3% of NPC patients were positive with a GMT of 1:7.3 and none of the normal individuals were positive. There was no difference in the detection of antibodies to EBV MA when other P3HR-1 or B95-8 cell lines, differing in their major membrane antigen, were used.

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