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Preservation of self: An overview of E3 ubiquitin ligases and T cell tolerance

✍ Scribed by J.M. Schartner; C.G. Fathman; C.M. Seroogy


Book ID
116885496
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
634 KB
Volume
19
Category
Article
ISSN
1044-5323

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E3 ubiquitin ligases in T-cell tolerance
✍ Magdalena Paolino; Josef M. Penninger πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 189 KB

## Abstract The immune system uses several mechanisms of central and peripheral tolerance in order to prevent the activation of T lymphocytes toward self‐antigens. Although the importance of immune self‐tolerance has been established for a long time, some essential cellular and molecular mechanisms