Preparative resolution of racemates on a chiral liquid chromatography column
β Scribed by Pirkle, William H.; Finn, John M.
- Book ID
- 126406261
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 423 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
## Abstract Fast resolutions of racemic compounds (sulfoxides, amino alcohols, and Ξ±βmethylarylacetic acids derivatives) were achieved on a chiral microbore column using carbon dioxide and a polar methanol/dioxane modifier. The stationary phase used in this study contains the 3,5βdinitrobenzoyl der
The direct resolution of racemic jasmonic acid (JA) and abscisic acid (ABA), as the free acids, into the corresponding enantiomers by high performance liquid chromatography on a Nucleodex p-PM column is reported. The resolution factors (R,,,=1.38; R,,,,=1.65) were such that the method could be appli
In the application of chromatography in preparative work, the sample load and the resoWion are the most importzmt characteristics. An equation describing both the sample Ioad and the chrom~to~aphic resolution as a function of the other process variables is derived. The in&xence of the selectivity co