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Preparation of tritiated 2,4-diamino-5-adamantyl-6-methylpyrimidine

✍ Scribed by Sigmund F. Zakrzewski; E. Anthony Evans

Book ID
102374596
Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
343 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Tritium labeled 2,4‐diamino‐5‐adamantyl‐6‐methylpyrimidine was prepared by a platinum metal catalyzed tritium exchange for 4 hr at 70°. The crude material was purified on a Sephadex G‐25 column and converted to its water soluble ethanesulfonate salt. The analysis of the purified material revealed that 43% of the tritium was located in the 6‐methyl group and the remainder in the adamantane moiety of the molecule.

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