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Preparation of Substituted Indolines via Anionic Cyclization

✍ Scribed by Bailey, William F.; Jiang, Xing-Long


Book ID
126407109
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
136 KB
Volume
61
Category
Article
ISSN
0022-3263

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Solid-phase synthesis of indolines via p
✍ Yongping Yu; John M Ostresh; Richard A Houghten πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 100 KB

The solid-phase synthesis of indolines from resin-bound 2-bromophenylacetylated amino acids is described. The exhaustive reduction of solid-support bound amides with borane afforded the requisite secondary amines that, following the palladium-catalyzed intramolecular cyclization and cleavage, provid